U.S. Route 60

Explore U.S. Route 60, a historic east–west highway spanning from Arizona to Virginia. Discover key cities, scenic routes, and its role in American transportation history.

U.S. Route 60 (US 60) is a major east–west United States highway that stretches over 2,600 miles from the deserts of Arizona to the Atlantic coast of Virginia. Originally part of the U.S. Highway System established in 1926, it serves as a vital corridor across the southern Midwest and Appalachia. Though it was once proposed to extend to Los Angeles, today the highway begins in western Arizona at an interchange with Interstate 10 near Brenda and ends in Virginia Beach, Virginia.

Traveling through a diverse cross-section of the country, US 60 passes through several major cities and regions, including Amarillo, Texas; Oklahoma City, Oklahoma; Springfield, Missouri; Lexington, Kentucky; and Charleston, West Virginia. In some areas, it parallels or overlaps with other major highways such as US 62, US 66 (in its historic alignments), and parts of Interstate 64. Along the way, US 60 transitions from desert landscapes to rolling plains, forested hills, and Appalachian mountain terrain, making it a route rich in scenic variety.

Historically, US Route 60 has played an essential role in facilitating regional commerce and cross-country travel. It remains heavily used in rural and urban areas alike. Numerous segments of US 60 have been upgraded to four-lane divided highways or freeways, particularly in Kentucky and West Virginia, where it serves as a key alternative to I-64. For road trip enthusiasts and transportation historians, US 60 offers a glimpse into both the historical development of America’s roadways and the continuing evolution of modern highway infrastructure.

Discover U.S. Routes

U.S. Route 60: Morganfield to Sturgis ~ Kentucky

U.S. Route 60: Morganfield to Sturgis ~ Kentucky

Experience a relaxed 10-mile drive along U.S. Route 60 from Morganfield to Sturgis, Kentucky, passing through rolling farmland, rural landscapes, and small-town history in the heart of Union County.

U.S. Highway 60: Henderson to Morganfield – Kentucky

U.S. Highway 60: Henderson to Morganfield – Kentucky

Travel 21 miles west along U.S. Highway 60 from Henderson to Morganfield, Kentucky, passing through Corydon, Waverly, and the Morganfield bypass. Explore small-town life and the rural charm of western Kentucky in this scenic drive.

U.S. Highway 60: Sturgis to Marion – Kentucky

U.S. Highway 60: Sturgis to Marion – Kentucky

Travel U.S. Highway 60 from Sturgis to Marion, Kentucky, for a 20-mile drive through scenic farmland, charming small towns, and local history. Explore roadside highlights, mining heritage, and the beauty of western Kentucky on this classic American highway.

U.S. Highway 60: Versailles to Lexington – Kentucky

U.S. Highway 60: Versailles to Lexington – Kentucky

Experience the beauty of Kentucky’s Bluegrass Region on U.S. Highway 60 from Versailles to Lexington. This 6-mile route features rolling pastures, legendary horse farms, the Lexington Blue Grass Airport, and quick access to historic bourbon country—all within a scen…

U.S. Route 60: Lexington to Versailles – Kentucky

U.S. Route 60: Lexington to Versailles – Kentucky

Drive six scenic miles along U.S. Route 60 from Lexington to Versailles, Kentucky, passing Lexington Blue Grass Airport and the picturesque horse farms of Bluegrass Country, before joining the Bluegrass Parkway.

U.S. Route 60: Sikeston to Poplar Bluff – Missouri

U.S. Route 60: Sikeston to Poplar Bluff – Missouri

Travel 51 miles west on U.S. Route 60 from Sikeston to Poplar Bluff, Missouri. This at-grade divided highway—partially upgraded to interstate standards—is a key connector through the Bootheel’s farmland and small towns like Dexter and Fisk.

U.S. Route 60: Afton to White Oak – Oklahoma

U.S. Route 60: Afton to White Oak – Oklahoma

Cruise 21 peaceful miles through rural Oklahoma on U.S. Route 60 from the Historic Ribbon Road near Afton to Oklahoma Highway 66 in White Oak. Explore the legacy of Route 66, prairie farmland, and small-town Americana in this scenic drive through northeastern Oklahoma.

U.S. Route 60: Westbound in Springfield – Missouri

U.S. Route 60: Westbound in Springfield – Missouri

Drive 8 miles through Springfield, Missouri along U.S. Route 60 and Missouri Highway 360. From the U.S. 65 interchange to Campbell Avenue and westward to Interstate 44, this short route reveals the city’s southern growth, retail hubs, and highway connections.