Take a scenic cruise around the Queen City as we follow the western loop of Interstate 275, a 43-mile semi-circular journey that skirts the hills and rivers around Cincinnati. This drive connects Ohio, Indiana, and Kentucky, offering a fast-moving glimpse of Cincinnati’s sprawling metro fringes, historic river towns, and rolling countryside.
Our adventure kicks off just north of Cincinnati proper, as we merge onto Interstate 275 from the busy corridor of Interstate 75. Immediately, the pace shifts from urban intensity to suburban sprawl. We soon pass the interchanges for U.S. 127 and U.S. 27, where access roads lead towards the western neighborhoods of Hamilton County and the smaller towns like Colerain Township. Despite the development around us, the route maintains a brisk, open feel, threading between retail parks, wooded patches, and the ever-present reminders of Cincinnati’s northern suburbs. The landscape begins to tilt westward as we approach the interchange with Interstate 74 near Miamitown, where the westbound flow of traffic merges and briefly doubles up, creating a more heavily traveled stretch.
Crossing the Great Miami River, the highway sheds some of its urban character, giving way to the broader floodplains and farmland marking the transition toward Indiana. At Exit 5, Interstate 74 peels away, leaving us to continue south along the quiet western loop of I-275. This section offers a much more relaxed atmosphere, interrupted only by a final Ohio interchange before the welcome sign ushers us into the Hoosier State. The countryside around Lawrenceburg opens up before us, revealing a small-town charm nestled along U.S. 50, with the shimmering waters of the Ohio River just to our east. The highway here is wide and smooth, making for a pleasant stretch of rural driving interrupted by the distant smokestacks of Lawrenceburg’s industry and the casino traffic from the riverfront.
As we cross the stately Ohio River via the Carroll C. Cropper Bridge, we leave Indiana behind and roll into Kentucky. The highway turns eastward now, curving around the southern periphery of Cincinnati’s metropolitan sprawl. We catch glimpses of the vast runway systems and sprawling grounds of Cincinnati/Northern Kentucky International Airport as we take the exit toward Hebron. This area stands in stark contrast to the sleepy towns we’ve passed, with hotels, logistics hubs, and warehouses reflecting the airport’s significant regional importance. Continuing east, we traverse a more developed suburban corridor as we approach Erlanger and the junction with Interstate 71 and Interstate 75. Our loop concludes in Kentucky, having fully encircled the western half of the Cincinnati metro, where the broad interchanges and flyover ramps once again signal our re-entry into the bustling flow of I-75.
Interstate 275’s western loop is more than just a bypass—it’s a journey through the outskirts of three states, a rapid shift from urban neighborhoods to rural tranquility and back to suburban bustle, all while tracing the natural and industrial veins that feed greater Cincinnati. Whether you’re bypassing downtown traffic or simply soaking in the cross-border charm of the Ohio Valley, this drive serves up a dynamic slice of America’s heartland.
🗺️ Route Map
Note: Due to OSM’s lack of waypoint support, the map above shows us starting and ending shy of I-75. We start and finish this video at I-75.





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